Bota Bio and Medichem Announce Partnership to Improve Sustainable Pharmaceutical Production

Bota Bio, a global industrial biotechnology company advancing sustainable biomanufacturing, and Medichem, a vertically integrated pharmaceutical company engaged in the process development and manufacture of active pharmaceutical ingredients (API) and finished dosage forms (FDF), announced a commercial development collaboration to improve sustainability while reducing API manufacturing costs.
Under the terms of the agreement, Bota Bio and Medichem will work together to advance two high-value API programmes. Bota Bio will develop novel enzymes to catalyse efficient, environmentally sustainable manufacturing procedures that reduce the use of expensive reagents and intermediates. Medichem will be in charge of the API's research, scale-up, manufacture, and commercialisation from its facilities in Spain and Malta.
Cheryl Cui, PhD, co-founder and CEO of Bota Bio, said:
"We are delighted to work with Medichem, a company with more than 50 years of experience innovating in API and FDF development, production, and commercialisation. Bota Bio's technology platform leverages the power of biology to bring innovative solutions to our customers, enabling sustainable manufacturing of industrial products, including APIs. This project will also highlight Bota Bio and Medichem’s commitments to environmental sustainability.”
Jose Luis Rodriguez Miranda, Chief Operations Officer at Medichem, said:
"The pharmaceutical industry increasingly demands sustainable ways to manufacture important active ingredients. Enzymes provide an excellent solution. However, they are not yet broadly used given the low activity and in-process stability of unengineered enzymes. We are pleased to secure this innovative collaboration with Bota Bio, as Bota Bio has assembled an industry-leading enzyme-engineering team with a track record of transformative improvements in pharmaceutical manufacturing.
"We believe that the innovative biocatalytic processes enabled by Bota Bio developed enzymes will help optimise manufacturing while playing an important role in meeting our environmental sustainability goals.”
Source: Bota Bio